Hybrid systems are heterogeneous systems that exhibit both continuous and discrete dynamics. Over the last eight years we have focused on the development of systematic, real-time, predictive controller synthesis techniques for hybrid systems with constraints. In this talk I will first summarize our theoretical efforts starting from constrained optimal control design for hybrid systems with constraints. Then, I will show how these results can be used in order to develop a theory for distributed predictive control for large-scale systems. The second part of the talk presents a range of applications where the proposed techniques were used with great benefit. In particular I will present the concept of predictive and adaptive autonomy for vehicle dynamics control and its potential application to energy efficient building control systems. For more information about this seminar, please contact: JoAnne Lambert 510.486.4835, or send e-mail to JMLambert@lbl.gov